Download Catalytic Antibodies by Ehud Keinan PDF

By Ehud Keinan

Exploiting the inherent combinatorial mechanism within the biosynthesis of antibodies, a virtually unlimited number of biocatalysts might be generated. Catalytic antibodies are able to appearing nearly any form of response with excessive selectivity and stereospecificity.
the following, the pioneers within the use of catalytic antibodies assessment the whole scope of this interdisciplinary box, masking such themes as:
* theoretical features of constitution, mechanism and kinetics
* useful issues, from immunization recommendations to screening methods
* in vitro evolution and different smooth approaches
* functions from natural synthesis to scientific uses.
subsidized by way of the prime experts in antibody catalysis, this is often the 1st e-book to supply such complete insurance and constitutes a major reference for biochemists, natural chemists, biotechnologists and biomedical researchers.

Show description

Read or Download Catalytic Antibodies PDF

Similar clinical chemistry books

Asymmetric Synthesis with Chemical and Biological Methods

Edited by means of of the top researchers within the box, this booklet presents a deep, interdisciplinary perception into stoichiometric and catalytic reactions during this always increasing region. A plethora of most sensible German scientists with a global recognition covers a variety of features, from classical natural chemistry to strategy improvement, and from the theoretical historical past to organic tools utilizing enzymes.

Handbook of C-H Transformations [organic chemistry

Right here, the total diversity of the functionalization of CH-bonds is gifted for the 1st time in a single guide, with the focal point all through on topicality and practicability. issues span glossy catalysts for Friedel-Crafts variety reactions to transition steel catalysts for the oxofunctionalization, through new equipment for radicalic halogenation to domino procedures through catalytic ortho metalation.

Theory and Applications of Computational Chemistry: The First Forty Years

Computational chemistry is a method of utilising theoretical principles utilizing pcs and a suite of ideas for investigating chemical difficulties in which universal questions fluctuate from molecular geometry to the actual homes of gear. thought and functions of Computational Chemistry: the 1st 40 Years is a set of articles at the emergence of computational chemistry.

Encyclopedia of Computational Chemistry, 5 Volume Set

Comprises 500 advanced illustrations in complete colour. * Thorough move referencing and Definition Entries (one paragraph dictionary articles). * Reference checklist includes not just conventional fabric, but in addition FTP and HTTP websites and related entries to digital resources. * Contributions from greater than three hundred best computational chemists.

Extra info for Catalytic Antibodies

Sample text

Lerner, R. , Angew. Chem. Int. Ed. 41 (2002), p. , Nature 271 (1978), p. , Steps Towards Life, a Perspective on Evolution, Oxford University Press, Oxford 1992 Burnet, F. , The Clonal Selection Theory of Aquired Immunity, Cambridge University Press, Cambridge 1959 Talmage, D. , Science 129 (1959), p. , Nature 302 (1983), p. 575–81 Janeway Jr, C. , London 1997 Jacobsen, J. , Prudent, J. , Schultz, P. , Science 256 (1992), p. , Ashley, J. , Benkovic, S. , Janda, K. , Lerner, R. , Science 252 (1991), p.

Biochemistry 36 (1997), p. , J. Biol. Chem. 274 (1999), p. , Benkovic, S. J. Biochemistry 28 (1989), p. 6611–6618 Stemmer, W. , Nature 370 (1994), p. 389–91 Orencia, M. , Yoon, J. , Ness, J. , Stemmer, W. , Stevens, R. , Nat Struct Biol 8 (2001), p. 238–42 Koshland, D. , Jr. Cold Spring Harb. Symp. Quant. Biol. 52 (1987), p. 1–7 Andrews, P. , Smith, G. , Young, I. , Biochemistry 12 (1973), p. 3492–8 Driggers, E. , Cho, H. , Liu, C. , Katzka, C. , Braisted, A. , Ulrich, H. , Wemmer, D. , Schultz, P.

1929–33 Romesberg, F. , Schultz, P. , Bioorg. Med. Chem. Lett. 9 (1999), p. 1741–4 Ulrich, H. , Santarsiero, B. , Driggers, E. , Stevens, R. , Schultz, P. , Nature 389 (1997), p. 271–5 Mundorff, E. , Hanson, M. , Schultz, P. , and Stevens, R. , Biochemistry 39 (2000), p. 627–32 Hsieh, L. , Stephans, J. , Schultz, P. , J. Am. Chem. Soc. 116 (1994), p. 2167–2168 References 25 Hsieh-Wilson, L. , Schultz, P. , 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 Stevens, R. , Proc. Natl. Acad. Sci. USA 93 (1996), p.

Download PDF sample

Rated 4.66 of 5 – based on 42 votes