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By Karl Maramorosch

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Kuroda INTRODUCTION Drosophila has been one of the most extensively studied materials from the viewpoint of genetics and cytology since Morgan (1910) discovered the first mutant of Drosophila, white eye. Recently it has also been chosen as a suitable material for studying many aspects of developmental biology, behavior, and molecular genetics. In vitro cultivation of cells and organs from Drosophila may provide as excellent procedure for investigating the p r o cess of growth and differentiation of embryonic cells and imaginai discs and for analyzing the tissue and time specificity of phenotypic expression of some mutant genes under strictly controlled conditions.

67, 432-446. Gilmour, D. (1961). "The Biochemistry of Insects," pp. 1-343. Academic Press, New York. Grace, T. D. C , and Brzostowski, H. W. (1966). J. Insect. Physiol. 12, 625-633. Hink, W. , Richardson, B. , Schenk, D. , and Ellis, B. , (1973). Proc. 3rd Intern. Colloq. Invertebr. Tissue Culture, pp. 195-208. Landureau, J. , and J o l i e s , P. (1969). Exp. Cell Res. 54, 391-398. D e t e r m i n a t i o n of Essential A m i n o A c i d s 51 Mitsuhashi, J. (1972). Appl. Entomol. Zool. 7, 39-41.

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